Description
Why It’s Done:
This test is done to:
• Diagnose infectious mononucleosis in individuals with symptoms such as:
o Fever
o Sore throat
o Swollen lymph nodes
o Fatigue
o Enlarged spleen or liver
• Differentiate IM from other causes of similar symptoms, such as strep throat or cytomegalovirus (CMV).
• Support diagnosis when Epstein-Barr virus antibody tests or CBC results are inconclusive.
Note: The test is most reliable after the first week of symptoms. False negatives may occur early in infection or in young children.
Preparation:
• No fasting or special preparation is needed.
• A blood sample is taken from a vein in your arm.
• Inform your doctor about:
o Recent symptoms (duration, severity).
o Medications you are taking.
o Any history of immune system disorders.


