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Smith (Sm) Igg Antibodies – Immuno Blot

₹1,050.00

15 minutes
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The Smith (Sm) IgG Antibodies Immuno Blot test is a diagnostic blood test used to detect autoantibodies specifically targeting Smith (Sm) antigens. These antigens are proteins found in the nucleus of cells, and the presence of antibodies against these antigens is strongly associated with systemic lupus erythematosus (SLE), an autoimmune disease. The test is commonly used to aid in the diagnosis of SLE and to help distinguish it from other autoimmune conditions. The Immuno Blot technique is a highly sensitive method for detecting specific antibodies in the blood, making it a reliable tool for identifying these autoantibodies.

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    Description

    Purpose of the Test:
    • Diagnose systemic lupus erythematosus (SLE), particularly when the diagnosis is uncertain
    • Detect Sm antibodies, which are considered a hallmark for diagnosing lupus
    • Help differentiate SLE from other autoimmune disorders, as Sm antibodies are relatively specific to lupus
    • Monitor the progression of lupus and its activity by tracking antibody levels over time
    • Assess autoimmune disease activity in patients with suspected or known SLE

    What the Test Involves:
    • A blood sample is drawn from a vein in your arm
    • The sample is tested using the Immuno Blot method, which involves separating the blood proteins, then detecting the specific Sm IgG antibodies through a blotting technique that identifies the binding of the antibody to the Sm antigens
    • The presence of Sm IgG antibodies in the blood indicates a higher likelihood of systemic lupus erythematosus (SLE)
    • The test is highly specific, meaning it helps distinguish SLE from other autoimmune conditions like rheumatoid arthritis or scleroderma, which may present with similar symptoms

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