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Philadelphia Chromosome / Bcr-Abl – Qualitative

₹4,500.00

15 minutes
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The Philadelphia Chromosome BCR-ABL – Qualitative Test is a genetic test used to detect the presence of the BCR-ABL fusion gene, which is associated with certain types of leukemia, particularly chronic myelogenous leukemia (CML). This fusion gene is formed when a part of chromosome 9 and chromosome 22 break and reattach, leading to the production of an abnormal protein that causes cancerous cell growth.
This is a qualitative test, meaning it determines whether or not the BCR-ABL gene is present but does not measure the quantity of the gene.

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    Description

    Why It’s Done
    This test is primarily used to:
    • Diagnose chronic myelogenous leukemia (CML) and other related cancers, such as acute lymphoblastic leukemia (ALL).
    • Confirm the presence of the Philadelphia chromosome, which helps identify CML in patients with symptoms like fatigue, unexplained weight loss, and an enlarged spleen.
    • Monitor treatment in patients with CML to ensure that therapies (like tyrosine kinase inhibitors) are effectively targeting the BCR-ABL protein.
    • Assess relapse risk or response to treatment, as the BCR-ABL gene can help track disease progression.

    Preparation
    • No special preparation is required for this test.
    • Blood sample: The test is usually performed using a blood sample, which is drawn from a vein in your arm. In some cases, a bone marrow sample may be required if the blood test is inconclusive.
    • Inform your doctor about any medications or treatments you are receiving, as certain therapies can influence the results.

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