Description
Why It’s Done
The DRVVT Test is typically done to:
• Diagnose lupus anticoagulant: Lupus anticoagulants are antibodies that can be associated with autoimmune diseases, particularly systemic lupus erythematosus (SLE). They can interfere with normal blood clotting and increase the risk of blood clots in veins and arteries, a condition known as antiphospholipid syndrome.
• Evaluate risk of thrombosis: Lupus anticoagulants can increase the risk of developing abnormal blood clots, leading to conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), stroke, or miscarriages. The DRVVT test helps in assessing this risk.
• Monitor patients with autoimmune conditions: It can be used in patients with suspected autoimmune disorders, such as lupus, to evaluate their risk for clotting problems.
• Confirm or rule out a diagnosis of antiphospholipid syndrome (APS): APS is an autoimmune disorder characterized by the presence of lupus anticoagulants and an increased tendency for clotting. The DRVVT test, when positive, helps in diagnosing APS.
• Assess effectiveness of anticoagulant therapy: In some cases, the DRVVT test may be used to assess the effectiveness of anticoagulant treatment in patients who are at high risk for clotting.
Preparation
• Medication history: Inform your healthcare provider about all medications you are currently taking, especially anticoagulants (like warfarin, heparin, or aspirin), as they can affect the results of the test.
• Avoid blood thinners: You may be asked to temporarily stop taking certain blood-thinning medications before the test. However, never stop your medication without first consulting your doctor.
• No special fasting requirements: Typically, fasting is not required for this test, but it’s important to follow any specific instructions given by your healthcare provider.
• Timing: The test is usually performed when a healthcare provider suspects an autoimmune disorder, so there is no specific timing requirement other than during active investigation of symptoms.
• Hydration: Being adequately hydrated is helpful for a blood draw, so it’s good to drink plenty of water before the test, but avoid excessive drinking right before the test.
