Calcium Total & Ionized Serum

1,000.00

The Calcium Total & Ionized Serum Test measures the amount of calcium in your blood in two forms:
1. Total Calcium: Includes both:
o Bound calcium (mostly attached to proteins like albumin)
o Free (ionized) calcium
2. Ionized Calcium: The active, free calcium in the blood that is not attached to proteins. This form is physiologically important because it is involved in:
o Nerve conduction
o Muscle contraction
o Blood clotting
o Enzyme function
Measuring both total and ionized calcium provides a more accurate picture of calcium status, especially in critically ill patients or those with abnormal protein levels.

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    Description

    Why It’s Done

    1. To Evaluate Calcium Imbalance
    • Hypercalcemia (high calcium levels)
    • Hypocalcemia (low calcium levels)
    These imbalances can be related to:
    • Parathyroid gland disorders
    • Kidney disease
    • Vitamin D deficiency or excess
    • Certain cancers
    • Bone diseases
    2. To Monitor Specific Conditions
    • Chronic kidney disease
    • Liver disease
    • Pancreatitis
    • After major surgeries or transfusions
    3. To Assess Function of Organs and Systems
    • Parathyroid hormone (PTH) activity
    • Bone health
    • Neuromuscular function
    4. To Monitor Therapy
    • Calcium or vitamin D supplements
    • Dialysis
    • Treatment for calcium-related disorders

    Preparation

    1. General Guidelines
    • Fasting: May be required (usually 8–12 hours) if the test is done along with other blood tests.
    • Medication: Inform your doctor about any medications or supplements you are taking, especially:
    o Calcium supplements
    o Vitamin D
    o Diuretics
    o Antacids
    o Lithium
    o Bisphosphonates
    Do not stop any medication unless advised by your healthcare provider.
    2. Avoid Certain Factors
    • Avoid vigorous exercise before the test as it may temporarily increase calcium levels.
    • Avoid a high-calcium meal or supplement within 12 hours if instructed by your doctor.
    3. Sample Collection
    • A blood sample is drawn from a vein in your arm.
    • For ionized calcium, the sample must be handled quickly and properly to avoid false readings (pH and temperature affect ionized calcium levels).
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