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Anti Chromatin Antibodies

₹2,000.00

15 minutes
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The Anti-Chromatin Antibodies test (also known as Anti-Nucleosome Antibodies test) is a blood test used to detect autoantibodies that target chromatin—a complex of DNA and proteins (including histones) found in the nucleus of cells.
This test is part of a group of autoimmune diagnostic tests and is particularly associated with systemic autoimmune disorders, especially Systemic Lupus Erythematosus (SLE). The presence of anti-chromatin antibodies indicates an abnormal immune response where the body attacks its own nuclear material.

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    Description

    Why It’s Done:

    Doctors may order this test to:
    • Diagnose or support a diagnosis of SLE (Systemic Lupus Erythematosus), especially when other antibody tests (like ANA or anti-dsDNA) are inconclusive.
    • Differentiate SLE from other autoimmune conditions such as:
    o Rheumatoid arthritis (RA)
    o Drug-induced lupus
    o Mixed connective tissue disease
    • Monitor disease activity or assess relapse in known SLE patients
    Anti-chromatin antibodies are often found in people with active SLE, especially those with kidney involvement (lupus nephritis).

    Preparation:

    • No special preparation is required for this test.
    • No fasting is needed.
    • Inform your doctor about:
    o Any current medications or supplements you are taking
    o Any diagnosed autoimmune conditions
    o Family history of autoimmune diseases

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