Description
Why It’s Done
The ANA – IFA test is mainly used to:
• Help diagnose autoimmune diseases, especially when symptoms suggest:
o Systemic Lupus Erythematosus (SLE)
o Sjögren’s Syndrome
o Scleroderma
o Mixed Connective Tissue Disease
o Polymyositis/Dermatomyositis
• Evaluate unexplained symptoms such as:
o Persistent joint pain or swelling
o Chronic fatigue
o Skin rashes (especially butterfly-shaped rash on the face)
o Recurrent fevers
• Monitor disease activity or response to treatment in diagnosed autoimmune conditions
Preparation for the Test
• Fasting: Not required.
• Medications: Inform your healthcare provider about any medications or supplements, as some can influence immune system activity.
• No special preparation is generally needed.
• Medical history: Providing a thorough medical history helps interpret results accurately


