Description
Why It’s Done
The F-18 NOTA-NOC PET CT scan is primarily used for the diagnosis, staging, and follow-up of neuroendocrine tumors, including:
• Carcinoid tumors
• Pancreatic neuroendocrine tumors (PNETs)
• Pheochromocytomas and paragangliomas
• Medullary thyroid carcinoma
• Other NETs of unknown primary origin
Clinical purposes include:
• Detecting primary and metastatic lesions
• Assessing somatostatin receptor status to determine eligibility for peptide receptor radionuclide therapy (PRRT)
• Evaluating recurrence or progression
• Monitoring treatment response
This scan provides both functional and anatomical data, making it a vital tool in the management of NETs.
Preparation
Follow these preparation steps to ensure accurate and safe imaging:
1. Fasting:
• Fast for 4–6 hours before the scan (only plain water allowed).
• Avoid high-protein or high-fat meals the day before the test.
2. Medications:
• Continue your regular medications unless instructed otherwise.
• If you are on somatostatin analog therapy (e.g., octreotide, lanreotide), inform your physician. A temporary pause before the scan may be recommended.
3. Hydration:
• Drink plenty of water before and after the scan. Staying hydrated helps with radiotracer distribution and elimination.
4. Physical Activity:
• Avoid intense exercise for 24 hours before the scan.
5. Clothing:
• Wear comfortable, metal-free clothing. You may need to change into a hospital gown.
• Remove all jewelry, belts, and metal objects before the scan.
6. Inform Your Provider If:
• You are pregnant, breastfeeding, or may be pregnant.
• You have kidney issues or a history of allergic reactions to imaging agents


