Description
Why It’s Done:
The Fetal Cord Blood Cytogenetics by FISH test is done for:
• Early detection of chromosomal abnormalities in the fetus, especially in pregnancies at higher risk for genetic conditions.
• Confirm or rule out conditions like Down syndrome, Edwards syndrome, and Patau syndrome through direct analysis of fetal chromosomes.
• Investigate unexplained pregnancy complications, such as miscarriage, fetal growth restriction, or abnormal ultrasound findings.
• Prenatal diagnosis for families with a history of genetic disorders or known chromosomal abnormalities.
• Support decision-making for further management or treatment options during pregnancy.
Preparation:
• Sample Collection: The test requires a sample of cord blood, which is typically obtained during an amniocentesis or chorionic villus sampling (CVS) procedure, though it may also be collected directly from the umbilical cord during delivery if necessary.
• Timing: This test is usually performed after 16 weeks of gestation when the fetus’s cells can be reliably analyzed.
• Fasting: Not required for this test.
• Medications: Inform your healthcare provider about any medications you’re taking, as some may affect the results or procedure.
• Consent: You may need to provide informed consent for the procedure that involves obtaining fetal blood, which carries some risk (such as miscarriage or infection).
• Pre-Test Counseling: Genetic counseling is often recommended before undergoing testing to understand the potential risks and benefits.
