Description
Why It’s Done
This test may be ordered if you:
• Have experienced unexplained blood clots (especially deep vein thrombosis or pulmonary embolism).
• Have a family history of thrombophilia or known prothrombin gene mutation.
• Have had recurrent miscarriages, particularly in the second or third trimester.
• Are planning hormonal therapy (e.g., oral contraceptives or hormone replacement therapy) and have a clotting history.
• Are undergoing surgery or prolonged immobilization and have a personal/family history of clotting disorders.
The results help assess your risk of developing blood clots and may guide treatment or lifestyle recommendations.
Preparation
• No special preparation is typically needed.
• Inform your doctor if you’ve had a recent blood transfusion, as it might affect the test results.
• Genetic counseling may be recommended before and after the test to understand the implications of the results.


