Description
Why It’s Done:
This test is performed to:
• Monitor exposure to bismuth, especially in individuals taking bismuth-containing medications long-term
• Detect bismuth toxicity, which can cause symptoms such as:
o Confusion or memory problems
o Tremors
o Kidney dysfunction
o Gum discoloration or oral lesions
• Assess kidney function in eliminating bismuth from the body
Bismuth accumulation may occur in individuals with impaired kidney function or after prolonged use of bismuth-based compounds.
Preparation:
• No special dietary restrictions are usually required unless instructed by your doctor.
• You may need to stop taking medications or supplements containing bismuth before the test (only under medical supervision).
• The test involves collecting all urine for 24 hours:
1. Discard the first urine of the day.
2. Collect all subsequent urine in a provided container for the next 24 hours, including the first urine of the following morning.
• Store the container in a cool place (usually a refrigerator or cooler) during the collection period.
• Follow all instructions provided by your healthcare provider or laboratory carefully


