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Sucrose Lysis Test

₹750.00

15 minutes
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The Sucrose Lysis Test is a screening test used primarily to detect Paroxysmal Nocturnal Hemoglobinuria (PNH), a rare acquired blood disorder. The test evaluates the sensitivity of red blood cells (RBCs) to lysis (destruction) when exposed to a low ionic strength sucrose solution, which promotes complement activation.

Description

Purpose of the Test:
• Screen for Paroxysmal Nocturnal Hemoglobinuria (PNH)
• Identify complement-sensitive red blood cells
• Support diagnosis in patients with unexplained hemolytic anemia, hemoglobinuria, or bone marrow failure

What the Test Involves:
• A blood sample is collected from the patient
• The RBCs are incubated in a sucrose solution
• The solution enhances complement binding, and increased hemolysis indicates PNH or a related condition

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