Description
Purpose of the Test:
• Screen for Paroxysmal Nocturnal Hemoglobinuria (PNH)
• Identify complement-sensitive red blood cells
• Support diagnosis in patients with unexplained hemolytic anemia, hemoglobinuria, or bone marrow failure
What the Test Involves:
• A blood sample is collected from the patient
• The RBCs are incubated in a sucrose solution
• The solution enhances complement binding, and increased hemolysis indicates PNH or a related condition


