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Intrinsic Factor Ab

₹6,000.00

15 minutes
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The Intrinsic Factor Antibody (IF Ab) test is a blood test used to detect antibodies against Intrinsic Factor (IF), a protein produced in the stomach. Intrinsic Factor is essential for the absorption of vitamin B12 in the small intestine. The presence of Intrinsic Factor antibodies can interfere with the absorption of vitamin B12 and is often associated with pernicious anemia, a condition in which the body cannot properly absorb vitamin B12 from the digestive tract.
This test helps determine if the cause of vitamin B12 deficiency is due to the presence of these antibodies, which can affect the body’s ability to absorb the vitamin and lead to anemia and other neurological symptoms.

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    Description

    Why It’s Done:
    • To diagnose pernicious anemia: The presence of Intrinsic Factor antibodies is a key marker for pernicious anemia, a type of megaloblastic anemia caused by vitamin B12 deficiency.
    • To investigate B12 deficiency: It helps to determine whether a vitamin B12 deficiency is due to autoimmune causes, such as pernicious anemia, or due to dietary factors or other conditions.
    • To confirm autoimmune involvement: The test is helpful when low B12 levels are detected, but the cause of the deficiency is unclear. It helps differentiate between different causes of vitamin B12 deficiency.
    • To monitor treatment: If a patient has been diagnosed with pernicious anemia, the test can be used to monitor the presence of antibodies over time, especially if there are concerns about the effectiveness of treatment or recurrence of the condition.

    Preparation:
    • Fasting is not typically required, but it’s important to follow any instructions provided by your healthcare provider.
    • A blood sample is taken, typically from a vein in your arm.
    • Inform your healthcare provider about any vitamin B12 supplements or medications you may be taking, as these can affect B12 levels and potentially influence the results.
    • No special preparations are needed, but your doctor may ask you to have this test along with other tests to measure your vitamin B12 levels and assess your overall health.

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