Description
Why It’s Done:
This test panel is used to:
• Determine hormone receptor status (ER/PR) to guide hormonal therapy decisions.
• Evaluate HER2 status, which is critical for selecting HER2-targeted therapies such as trastuzumab.
• Assess DNA ploidy, an indicator of tumor cell genomic stability — aneuploid tumors tend to behave more aggressively and may be associated with poorer prognosis.
• Support personalized treatment planning based on the biological characteristics of the tumor.
By combining receptor status with genetic profiling (DNA content), the test offers a more comprehensive assessment of breast cancer prognosis.
Preparation:
• No special preparation is required from the patient.
• The test is performed on tissue samples obtained via biopsy or surgical removal of the tumor.
• If undergoing a biopsy, the healthcare provider may provide instructions related to fasting, medications, or other pre-procedure requirements


