Description
Why It’s Done:
This test is ordered when there is a need to:
• Differentiate between adenocarcinoma and mesothelioma, especially in cases involving pleural or peritoneal tumors.
• Provide a definitive diagnosis to guide appropriate treatment.
• Aid in the classification of malignant pleural effusions or biopsies from serous membranes.
• Determine prognosis and therapeutic approach, since treatment strategies differ significantly between the two cancers.
Preparation:
• No special preparation is typically required for the IHC test itself.
• A biopsy is necessary to obtain tissue for testing. This may be from the pleura, peritoneum, or another affected site.
• Pre-biopsy instructions may include fasting or medication adjustments, depending on the procedure type.
• Inform your healthcare provider about any ongoing medications, allergies, or underlying health conditions.


