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Hla B27 (Flow Cytometry)

₹3,000.00

15 minutes
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The HLA-B27 test detects the presence or absence of the HLA-B27 protein, a specific human leukocyte antigen (HLA) found on white blood cells.
• This test uses flow cytometry, a laboratory technique that analyzes individual cells as they pass through a laser beam.
• Flow cytometry detects HLA-B27 on the cell surface by tagging it with fluorescent antibodies, offering rapid and accurate results.

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    Description

    Why It’s Done (Purpose):

    1. Diagnose Autoimmune Disorders:
    o Most commonly used to support the diagnosis of ankylosing spondylitis (AS) and other spondyloarthropathies, including:
     Reactive arthritis
     Psoriatic arthritis (axial type)
     Juvenile idiopathic arthritis (enthesitis-related type)
     Inflammatory bowel disease–related arthritis
    2. Assess Genetic Predisposition:
    o A positive result indicates a genetic predisposition but not a diagnosis on its own.
    o 90–95% of patients with ankylosing spondylitis are HLA-B27 positive, but many people with HLA-B27 never develop disease.
    3. Support Differential Diagnosis:
    o Helps differentiate inflammatory back pain from other causes (e.g., mechanical back pain or degenerative diseases).

    Preparation Guidelines:

    • No special preparation is required.
    • A blood sample is drawn from a vein.
    • Inform your healthcare provider of:
    o Any current infections or autoimmune symptoms.
    o Recent blood transfusions, as they may affect test accuracy.

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