Description
Why It’s Done:
This test is used to:
• Diagnose or monitor Wilson’s disease, a rare inherited disorder where copper accumulates in the liver, brain, and other organs.
• Help diagnose Menkes disease, a rare genetic disorder that affects copper levels in the body.
• Evaluate copper deficiency or copper toxicity.
• Monitor patients receiving nutritional supplementation or parenteral nutrition (IV feeding).
• Investigate unexplained neurological symptoms or liver problems.
It is often ordered along with ceruloplasmin levels or 24-hour urine copper test for a more accurate assessment.
Preparation:
• Fasting may be required for 8–12 hours before the test, depending on the lab’s protocols.
• Avoid taking mineral supplements (especially copper, zinc, or iron) for at least 24 hours prior to the test unless instructed otherwise by your doctor.
• Inform your healthcare provider about all medications and supplements you are using.
• The test is performed using a blood sample, usually taken from a vein in the arm.


