Description
Why It’s Done:
This test is commonly ordered to:
• Monitor cobalt exposure in individuals with metal-on-metal hip implants or those working in industries involving cobalt (e.g., mining, metalwork).
• Investigate symptoms of cobalt toxicity, such as:
o Hearing or vision problems
o Neurological symptoms (e.g., weakness, numbness, tremors)
o Heart problems (e.g., cardiomyopathy)
o Thyroid dysfunction
• Evaluate environmental or occupational exposure.
• Rule out heavy metal poisoning in patients with non-specific symptoms.
Preparation:
• No fasting is required, but follow all instructions from your healthcare provider.
• Avoid vitamin or mineral supplements (especially those containing B12 or cobalt) for at least 24 hours before and during the test, unless advised otherwise.
• You will be provided with a special collection container to collect all urine over a 24-hour period.
o Start by discarding the first morning urine.
o Collect all urine for the next 24 hours, including the first urine the following morning.
o Keep the container refrigerated or on ice during the collection.
• Inform your doctor about any medications or recent imaging tests with contrast dye, which may interfere with results.
