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Cd 3 (Pan-T Cell)

₹3,000.00

15 minutes
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The CD3 (Pan-T Cell) Test is a laboratory test that identifies and measures the CD3+ T-cells in a blood or tissue sample. CD3 is a protein complex that is found on the surface of all T-lymphocytes (T-cells), which are a crucial part of the immune system involved in recognizing and responding to foreign invaders, such as viruses, bacteria, and abnormal cells like tumors.
The Pan-T Cell test refers to the identification of all T-cells in the blood because CD3 is a marker that is expressed by virtually all T-cells, both helper T-cells (CD4+) and cytotoxic T-cells (CD8+). The test is performed using flow cytometry, a technique that allows for precise enumeration and analysis of T-cells.

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    Description

    Why It’s Done:

    The CD3 (Pan-T Cell) test is performed for several key reasons:
    • Monitor immune system function, particularly in individuals with autoimmune diseases, immunodeficiencies, or HIV/AIDS, where T-cell counts are a key indicator of immune health.
    • Assess T-cell population in patients undergoing organ or stem cell transplantation to evaluate the immune system’s recovery or to monitor for graft-versus-host disease (GVHD).
    • Diagnose T-cell related malignancies, such as T-cell leukemia or T-cell lymphoma, where abnormalities in the T-cell population may be detected.
    • Evaluate immune responses in conditions that affect T-cell activity, such as chronic infections, autoimmune diseases, or transplant rejection.
    • Monitor treatment effectiveness in patients receiving immunotherapy, chemotherapy, or immunosuppressive drugs, as these can impact T-cell counts and function.

    Preparation:

    • No fasting or special preparation is typically required for the CD3 test.
    • Inform your healthcare provider about any medications, particularly immunosuppressive drugs or chemotherapy, as they may affect T-cell levels.
    • A blood sample is collected from a vein in your arm, and it is then processed using flow cytometry to analyze the CD3+ T-cell population.

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