Description
Why It’s Done:
The CD22 percent test is performed for several key reasons:
• Diagnosing and monitoring B-cell malignancies such as B-cell lymphoma and chronic lymphocytic leukemia (CLL), where the proportion of CD22+ cells can be abnormal.
• Investigating immune system disorders, particularly those affecting B-cells, to assess the balance and functionality of the immune system.
• Evaluating autoimmune diseases where B-cells may be involved in the disease process.
• Monitoring treatment efficacy in patients with B-cell cancers, such as non-Hodgkin lymphoma, to evaluate changes in the proportion of B-cells.
• Identifying B-cell deficiencies in immunodeficiencies or conditions like X-linked agammaglobulinemia, where B-cells may be deficient or absent.
Preparation:
• No special preparation is typically required for this test.
• Inform your healthcare provider about any medications, especially those that may impact immune cell function (e.g., immunosuppressive drugs, chemotherapy).
• A blood sample is drawn from a vein in your arm and sent to a lab for flow cytometry analysis.
