Cd 11c – Percent

3,000.00

The CD11c – Percent Test is a laboratory test that measures the percentage of CD11c+ cells in a blood or tissue sample. CD11c is a cell surface marker that is primarily expressed on myeloid cells, such as dendritic cells, monocytes, and neutrophils. It plays a role in immune cell adhesion and is involved in phagocytosis (the process of engulfing pathogens or debris).
This test is typically performed using flow cytometry, which allows for the precise identification and quantification of CD11c+ cells in the sample. The percentage of CD11c+ cells can help in evaluating immune function and diagnosing certain hematologic conditions.

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    Description

    Why It’s Done:

    The CD11c – Percent Test is used for several key purposes:
    • Diagnosing hematological conditions, such as chronic myelomonocytic leukemia (CMML), where CD11c+ cells may be increased or present in abnormal amounts.
    • Evaluating immune system function and monitoring immune responses, particularly in diseases that affect myeloid cell populations or dendritic cells.
    • Monitoring immune-related disorders like autoimmune diseases, inflammatory diseases, or infections, where changes in CD11c+ cell populations may be observed.
    • Differentiating between normal and abnormal immune cell populations, especially in cases of leukemia, myelodysplastic syndromes, or monocytic disorders, where CD11c can help identify malignant or altered cells.
    • Evaluating myeloid-related malignancies or conditions involving abnormal dendritic cells.

    Preparation:

    • No fasting or special preparation is required for this test.
    • Inform your healthcare provider about any medications, particularly those affecting immune function or chemotherapy drugs, as these can influence cell populations.
    • A blood sample is typically collected from a vein in your arm, and the sample is analyzed using flow cytometry to quantify CD11c+ cells.