Description
Why It’s Done
The test is typically ordered to:
• Diagnose or rule out pheochromocytoma – a rare tumor of the adrenal gland that causes excessive catecholamine production.
• Evaluate for neuroblastoma – a type of cancer that mostly affects children and originates in nerve tissue.
• Assess unexplained high blood pressure, especially if it’s severe or episodic (comes in bursts).
• Investigate symptoms such as:
o Rapid heartbeat
o Headaches
o Sweating
o Flushing
o Anxiety or panic attack-like symptoms
Preparation
Proper preparation is important to ensure accurate results. Here’s what typically needs to be done:
1. Medication and Substance Restrictions
Avoid or inform your doctor about the following at least 2-3 days before the test, as they can interfere with results:
• Medications: such as tricyclic antidepressants, beta blockers, decongestants, amphetamines, and MAO inhibitors.
• Caffeine, alcohol, and nicotine.
• Foods high in amines, such as:
o Bananas
o Chocolate
o Vanilla
o Citrus fruits
o Coffee and tea
Always follow your doctor’s instructions regarding medications. Do not stop taking any medication without medical advice.


