Description
Why It’s Done
This test is used to:
1. Assess Beta Cell Function
• To evaluate the residual insulin-producing capacity of the pancreas in people with diabetes or suspected beta cell dysfunction.
2. Differentiate Types of Diabetes
• Helps distinguish type 1 diabetes (where beta cell function is typically very low or absent) from type 2 diabetes.
3. Diagnose and Monitor Insulin-Secreting Tumors (Insulinomas)
• To assess abnormal insulin secretion in response to glucagon stimulation.
4. Guide Treatment Decisions
• To help doctors decide on the best treatment approach based on pancreatic function.
Preparation
1. Fasting
• You should fast for 8 to 12 hours before the test (no food or drink except water).
2. Medications
• Inform your healthcare provider about any medications, especially insulin or diabetes drugs, as they might affect test results.
3. Test Procedure
• Blood samples will be drawn before glucagon injection and at intervals after the injection (usually 6 minutes or as per protocol).
• Glucagon is administered by injection during the test.


