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Bcr – Abl Quantitative

₹7,000.00

15 minutes
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The BCR-ABL Quantitative Test is a molecular diagnostic test that measures the amount (level) of the BCR-ABL fusion gene transcript in the blood or bone marrow using quantitative polymerase chain reaction (qPCR). Unlike qualitative tests that only detect presence or absence, this test provides a numerical value that reflects the burden of leukemic cells producing the BCR-ABL fusion protein.
This test is essential for monitoring patients with:
• Chronic Myeloid Leukemia (CML)
• Philadelphia chromosome-positive Acute Lymphoblastic Leukemia (Ph+ ALL)
It helps track treatment response, especially to tyrosine kinase inhibitors (TKIs), and detect minimal residual disease (MRD) or relapse.

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    Description

    Why It’s Done:

    This test is done to:
    • Monitor disease progression or remission in patients receiving treatment for CML or Ph+ ALL
    • Assess treatment effectiveness, particularly with TKIs like imatinib, dasatinib, or nilotinib
    • Detect minimal residual disease that may indicate relapse
    • Guide treatment adjustments based on the level of BCR-ABL transcripts

    Preparation:

    • No special preparation such as fasting is required.
    • A blood sample is collected, typically from a vein.
    • Inform your healthcare provider about recent treatments or medications.
    • Regular testing intervals may be recommended to closely monitor disease status.

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