Asma / Anti Smooth Muscle Antibody With Titre – Ifa

4,000.00

The Anti-Smooth Muscle Antibody (ASMA) with Titre – IFA test is a blood test that detects and measures the level (titre) of autoantibodies directed against smooth muscle components in the body, especially in the liver. The test is performed using an Indirect Immunofluorescence Assay (IFA) technique, which involves observing antibody binding under a fluorescent microscope.
The inclusion of the titre provides information about the concentration or strength of these antibodies, which can be useful in diagnosing and monitoring autoimmune liver diseases, especially Autoimmune Hepatitis (Type 1).

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    Description

    Why It’s Done:

    This test is typically recommended when a doctor suspects autoimmune liver disease or unexplained liver inflammation. It is used to:
    • Diagnose Autoimmune Hepatitis (AIH), especially Type 1
    • Evaluate patients with elevated liver enzymes (ALT, AST)
    • Distinguish autoimmune hepatitis from other causes of liver dysfunction
    • Monitor disease activity or progression in autoimmune hepatitis
    • Support diagnosis of other autoimmune or connective tissue diseases
    The titre helps assess the significance of the antibody presence:
    • Higher titres are more suggestive of autoimmune hepatitis.
    • Low titres may be seen in other conditions or even healthy individuals and must be interpreted in clinical context.

    Preparation:

    • No special preparation is needed for this blood test.
    • A routine venous blood sample will be collected.
    • Inform your doctor about:
    o Medications you’re taking
    o Any autoimmune conditions, symptoms, or recent illnesses
    o Any family history of liver disease