Description
Why It’s Done:
This test is typically recommended when a doctor suspects autoimmune liver disease or unexplained liver inflammation. It is used to:
• Diagnose Autoimmune Hepatitis (AIH), especially Type 1
• Evaluate patients with elevated liver enzymes (ALT, AST)
• Distinguish autoimmune hepatitis from other causes of liver dysfunction
• Monitor disease activity or progression in autoimmune hepatitis
• Support diagnosis of other autoimmune or connective tissue diseases
The titre helps assess the significance of the antibody presence:
• Higher titres are more suggestive of autoimmune hepatitis.
• Low titres may be seen in other conditions or even healthy individuals and must be interpreted in clinical context.
Preparation:
• No special preparation is needed for this blood test.
• A routine venous blood sample will be collected.
• Inform your doctor about:
o Medications you’re taking
o Any autoimmune conditions, symptoms, or recent illnesses
o Any family history of liver disease


