Terminal Deoxynucleotidyl Transferase / Tdt

2,000.00

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The Terminal Deoxynucleotidyl Transferase (TdT) test is used to detect the presence of TdT enzyme activity in blood or bone marrow samples. TdT is an enzyme typically found in immature lymphoid cells and is used as a marker to help diagnose certain leukemias and lymphomas, particularly acute lymphoblastic leukemia (ALL).

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    Description

    Purpose of the Test:
    • Diagnose acute lymphoblastic leukemia (ALL), especially in T-cell ALL
    • Differentiate between lymphoid and myeloid leukemias
    • Help identify immature lymphoid cells in bone marrow or blood
    • Evaluate acute leukemia cases to help with classification

    What the Test Involves:
    • A blood or bone marrow sample is collected
    • The test detects TdT enzyme activity through immunohistochemistry (IHC) or flow cytometry
    • Positive TdT activity suggests immature lymphocytes, which are a hallmark of acute leukemia