Awaiting product image

T- Cell Gene Rearrangemant

₹9,000.00

15 minutes
Categories: ,

The T-Cell Gene Rearrangement Test is a molecular diagnostic test used to detect clonal T-cell populations, which may indicate the presence of T-cell lymphoproliferative disorders, such as T-cell lymphoma or leukemia. This test analyzes the unique rearrangements in T-cell receptor (TCR) genes, particularly the TCR gamma and beta chains, to distinguish between reactive (polyclonal) and neoplastic (monoclonal) T-cell proliferations.

Enquiry Here

    Description

    Purpose of the Test:
    • Detect clonal T-cell receptor gene rearrangements
    • Help diagnose T-cell lymphomas, including cutaneous T-cell lymphoma (CTCL) and T-cell acute lymphoblastic leukemia (T-ALL)
    • Differentiate between malignant and benign/reactive T-cell expansions
    • Monitor minimal residual disease (MRD) or relapse

    What the Test Involves:
    • A sample of blood, bone marrow, lymph node tissue, or skin biopsy is collected
    • Polymerase Chain Reaction (PCR) is used to amplify TCR gene segments
    • A monoclonal pattern suggests a neoplastic process, while a polyclonal pattern suggests a reactive process

    Related products