Description
Why It’s Done:
This test is commonly recommended to:
• Diagnose folate deficiency, which can cause megaloblastic anemia.
• Investigate unexplained fatigue, weakness, or irritability.
• Monitor patients with malnutrition, alcoholism, or conditions affecting nutrient absorption (e.g., celiac disease, Crohn’s disease).
• Evaluate pregnant women to ensure adequate folate levels, essential for fetal development and preventing neural tube defects.
• Monitor people on medications that may interfere with folate absorption (e.g., methotrexate, phenytoin).
Preparation:
• Fasting: Usually not required, but some doctors may recommend fasting for 6–8 hours depending on the lab’s protocol.
• Medications: Inform your doctor about any supplements or medications you’re taking, as they may affect results.
• Timing: Blood is typically drawn in the morning.
• Avoid recent vitamin intake (especially folic acid supplements) before the test unless advised otherwise, as this can cause falsely elevated levels.


