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Cytochemistry For Leukemias -Mpo

₹2,000.00

15 minutes
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The MPO (Myeloperoxidase) cytochemical stain is a laboratory test used to detect the presence of the myeloperoxidase enzyme in white blood cells, specifically myeloid cells. It is performed on bone marrow or peripheral blood smears to help differentiate myeloid leukemias (AML) from lymphoid leukemias (ALL). Cells of myeloid lineage will show a positive reaction to MPO staining, appearing brown or black under the microscope, whereas lymphoid cells typically do not.

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    Description

    Why It’s Done

    The MPO test is primarily used to:
    • Aid in the diagnosis of acute myeloid leukemia (AML).
    • Differentiate AML from acute lymphoblastic leukemia (ALL).
    • Evaluate patients with unexplained high white blood cell counts, anemia, thrombocytopenia, or other symptoms suggestive of leukemia.
    • Support other findings from bone marrow examination and flow cytometry in leukemia classification.
    This test is crucial in guiding proper treatment, as AML and ALL require different therapeutic approaches.

    Preparation

    • No special preparation is usually needed.
    • A blood sample or bone marrow aspirate will be collected by a healthcare provider.
    • Inform the healthcare provider about any medications being taken, recent infections, or prior cancer treatments, if applicable.

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