Description
Why It’s Done:
This test is performed when a central nervous system (CNS) infection is suspected. Common conditions include:
• Meningitis (inflammation of the membranes surrounding the brain and spinal cord)
• Encephalitis (inflammation of the brain)
• Brain or spinal cord abscess
• Post-neurosurgical infections
Symptoms that may lead to this test include:
• Severe headache
• High fever
• Neck stiffness
• Nausea or vomiting
• Confusion or altered mental status
• Seizures
• Sensitivity to light (photophobia)
Purpose of the test:
• Detect the presence and type of CNS infection.
• Identify the exact microorganism causing the infection.
• Guide targeted treatment with appropriate antibiotics or antifungals.
• Monitor treatment effectiveness in ongoing infections.
Preparation:
• The test requires a lumbar puncture (spinal tap) to collect CSF.
• Fasting is usually not required, but follow your doctor’s specific instructions.
• Inform your doctor of any current medications, especially blood thinners or antibiotics.
• You may need to lie still during and after the procedure to minimize the risk of post-procedure headache.
• Your healthcare provider will explain the risks, and you may be asked to sign a consent form before the procedure.


