Description
Why It’s Done
The CD10 test is primarily used to help diagnose and classify blood cancers, especially:
1. Acute Lymphoblastic Leukemia (ALL)
• CD10 is strongly expressed in most cases of B-cell ALL.
• Helps differentiate between B-cell and T-cell ALL.
2. Lymphomas
• CD10 expression is found in some non-Hodgkin lymphomas, particularly:
o Follicular lymphoma
o Burkitt lymphoma
o Diffuse large B-cell lymphoma (DLBCL)
3. Other Uses
• To monitor disease progression or response to treatment.
• To help distinguish malignant cells from normal cells.
• As part of an immunophenotyping panel in leukemia and lymphoma workups.
Preparation
Preparation for a CD10 test depends on the type of sample required:
1. Blood or Bone Marrow Sample (Flow Cytometry)
• No special preparation is usually needed.
• Inform your doctor of any medications or recent infections.
2. Tissue Biopsy (Immunohistochemistry)
• If a biopsy is required, follow the specific fasting or pre-procedure instructions provided by your doctor or laboratory.
3. General Guidelines
• Provide a complete medical history, especially if there’s a known or suspected blood cancer.
• Let your healthcare provider know about any recent chemotherapy or immunotherapy, as these may affect test results.
